Problem 5-Glomerular Filtration and Urine Formation The GFR is the volume of fil

Question

Problem 5-Glomerular Filtration and Urine Formation

The GFR is the volume of filtrate produced by both kidneys per minute. The GRA in women averages 115 ml/minute.

a) what is the GFR per hour? Per day?

b) if the total blood volume is 5.5 L , how often is the total blood volume filtered?

c) since 85% of the original glomerular ultrafiltrate is reabsorbed in the PCT, what is the folume that remains in the dct and collecting ducts.?

d) This amount is reabsorbed accordance with the body’s state of hydration and by hormones.

What is the amount?

Explanation / Answer

A)-Volume of filtrate produced by both kidneys per minute.
---Women = 115 mL/minute
---Men = 125 mL/minute
-Equivalent to 7.5 liters per min and180 Liters per day

B)-The total blood volume (5.5 Liters) is filtered about every 40 minutes.

C) --85% of glomerular ultrafiltrate is reabsorbed in early portion of nephron.
--15% remains to enter distal convoluted tubule and collecting duct.

D) -Obligatory water loss is 400 mL per day.
--When this amount is excreted, 99.8% of glomerular ultrafiltrate is reabsorbed.
--Under a normal state of hydration, 1.5 Liters is excreted meaning 99.2% of glomerular ultrafiltrate is reabsorbed.

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