What happens when a patient has a mutation in the accessory protein associated w

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What happens when a patient has a mutation in the accessory protein associated with keratin? Where are microtubules found in a cell? What is the role of centrosome in the formation of microtubule? Describe the structure of microtubule What is dynamic instability and what leads to dynamic instability of microtubules? How are microtubules stabilized in a cell? Name the four microtubules specific drugs and describe their action. What are these drugs used for the treatment of cancer? Draw the structure of motor proteins associated with microtubule and label the parts. Explain the movement of motor proteins on the microtubule Describe three experiments performed to prove that the motor proteins move on the microtubule Label the parts in the picture shown below. What are the motor proteins associate with ER and golgi membranes? What are the differences between cilia and flagella with respect to their size, location, functions and movements? Describe the arrangement of microtubules in cilia and flagella What is kartagener's syndrome Name the type of movements that actin is responsible for

Explanation / Answer

10). Keratins are a group of scaffolding cytoskeletal proteins present in all epithelial cells, within which they form networks of intermediate filaments and provide structural support to keratinocytes. Keratinocytes play a key role in maintaining integrity of skin. Any mutations in genes expressing keratins or the accessory protein associated with keratin would result in a variety of skin carcinomas.

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