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Starting with I-2 determine list by generation & number how many males have the

ID: 73766 • Letter: S

Question

Starting with I-2 determine list by generation & number how many males have the same Y-STR DNA profile. Start with generation II and work your way down to generation IV. A woman claims she was raped by male IV-6. She submits to a rape test and a Y-STR profile is generated. No reference Y-STR from IV-6 is available. Which other members in the family above could provide a Y-STR profile Explain your reason. The database indicated this Y-STR profile was found in 7 out of 245,000 incarcerated males. How frequent is this profile State your answer as a "one in statement" Round your answer off to the nearest whole number and show work.

Explanation / Answer

1. The same Y-STR DNA profiles from I-2 will be seen in the males II-6, III-8, IV-7 and IV-10.

2. The Y-STR profile from III-5 can be taken instead of IV-6 as these are male Y-chromosome-specific DNA profiles, which are which are inherited through paternal lines. III-5 is the father of IV-6 who will pass on the Y-STR DNA to the next generation.

3. The Y haplotype frequency is given by x/N formula, where x is the number of times haplotype is observed and N is the total number of haplotypes.

7/245000= 2.857 x 10-5

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