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protonated means that the drug is in its acid form (HA) and dissociated means th

ID: 721895 • Letter: P

Question

protonated means that the drug is in its acid form (HA) and dissociated means that the drug is in its dissociated form (A-). the pH of the stomach is about 1 or 2. the pH of the blood is about 7.4. given that a drug has a pKa of 4.2.
a. the drug is a weak acid that is protonated in the stomach and dissociated in the blood
b. the drug is a weak acid that is dissociated in the stomach and the blood
c. the drug is a strong acid that is protonated in the stomach and the blood
d. the drug is a weak acid that is dissociated in the stomach and protonated in the blood
e. the drug is a strong acid that is dissociated in the stomach and protonated in the blood

Explanation / Answer

drug is a weak acid as its pKa = 4.2 so, a. the drug is a weak acid that is protonated in the stomach and dissociated in the blood is correct