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Syndrome A is an autosomal recessive disorder. Mutations in Gene A cause Syndrom

ID: 71538 • Letter: S

Question

Syndrome A is an autosomal recessive disorder. Mutations in Gene A cause Syndrome A. Imagine the frequency of the Syndrome A mutation is 0.25 in population 1 (which lives in Place 1) and 0.32 in population 2 (which lives in Place 2). If a number of people from population 1 migrate to Place 2, so that 35% of the population in Place 2 has come from Place 1, and they all breed randomly, what do you expect the frequency of Syndrome A to be once the population reaches equilibrium?

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Explanation / Answer

P+q=1

(0.25)2 + (0.32)2 +2(0.25)(0.32)