For 20-22 . Consider the following DNA sequence of the non-template strand: 5’ A
ID: 71512 • Letter: F
Question
For 20-22. Consider the following DNA sequence of the non-template strand:
5’ ATGAAGTTTGGCTAA 3’
Each of the following sequences contain a type of mutation:
A) 5’ ATGAAGTTGGCTAA 3’
B) 5’ ATGAAGTTTAGCTAA 3’
C) 5’ ATGTAGTTTGGCTAA 3’
D) 5’ ATGAAGTTTGGTTAA 3’
Consult the CODON table on the last page of the test to answer the following questions:
20. Which of the following has a Silent mutation?
A) B) C) D) E) None
21. Which of the following has a Nonsense mutation?
A) B) C) D) E) None
22. Which of the following has a Frameshift mutation?
A) B) C) D) None
Explanation / Answer
20. Which of the following has a Silent mutation?
The correct answer is option D. 5’ ATGAAGTTTGGTTAA 3’
The amino acid in 4th position is changed to glycine after mutation and in the nontemplate strand it was glycine.
21. Which of the following has a Nonsense mutation?
The correct answer is option C 5’ ATGTAGTTTGGCTAA 3’
Lys present in the 2nd position in nontemplate strand is mutated to a stop codon in sequence C
22. Which of the following has a Frameshift mutation?
The correct answer is option A. 5’ ATGAAGTTGGCTAA 3’
Deletion of a base T leads to Frameshift
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