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For desmosomes, select the correct properties or functions associated with it: (

ID: 71438 • Letter: F

Question

For desmosomes, select the correct properties or functions associated with it:

(A) Shape and mechanical strength: contributor to the resistance of the whole epithelial sheet to stretching and tearing, and/or to its ability to change shape.
(B) Interacts with intermediate filaments at their cytoplasmic sides
(C) Allows epithelia to maintain solute gradients between their apical and basal sides.
(D) Interacts with actin filaments on their cytoplasmic sides
(E) contains transmembrane proteins of the cadherin family
(F) Signaling: recruits signaling molecules to its cytoplasmic side that convey information to the cell about its surroundings.
(G) contains transmembrane proteins of the integrin family
(H) Keeps the sheet anchored: mediates interaction of the cells with the basal lamina, or underlying extracellular matrix.
(I) Major source of adhesion between cells
(J) Brings the plasma membrane of adjacent cells into such close apposition that even small molecules can’t leak between the cells.

Explanation / Answer

The correct properties and function are:

(A) Shape and mechanical strength: contributor to the resistance of the whole epithelial sheet to stretching and tearing, and/or to its ability to change shape.

(B) Interacts with intermediate filaments at their cytoplasmic sides

(E) contains transmembrane proteins of the cadherin family

(F) Signaling: recruits signaling molecules to its cytoplasmic side that convey information to the cell about its surroundings.

(I) Major source of adhesion between cells

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