LQB481 - Week 7 Pre-Practical MCQ Quiz For certain questions there may be more t

Question

LQB481 - Week 7 Pre-Practical MCQ Quiz For certain questions there may be more than ONE correct answer In such cases, select ALL correct answers that apply. 1. Substrate-level phosphorylations play critical roles in generating energy (ATP) especially during anaerobic respiration. Choose the set of enzymes that catalyse substrate-level phosphorylation reactions (a) Pyruvate kinase, Creatine phosphokinase, ATP synthase, Succinyl COA (b) Succinyl CoA synthetase, Pyruvate kinase, Creatine phosphokinase, (c) Pyruvate kinase, Phosphoinositide 3-kinase, Acetyl CoA synthetase, man synthetase. Phosphoglycerate kinase. Phosphoglycerate kinase. osphoglycerate kinase, Pyruvate kinase, Succinyl CoA synthetase, ATP synthase. Creatine phosphokinase, Acetyl CoA synthetase, Phosphoglycerate kinase, Pyruvate kinase. (e)

Explanation / Answer

Ans= option b

i.e. succinyl CoA synthetase, pyruvate kinase, ceratine phosphokinase, phosphoglycerate kinase

Explanation

In glycolysis, i.e. first substrate level phosphorylation, 1,3- biphosphoglycerate is dephosphorylated via phosphoglycerate kinase, producing 3- phosphoglycerate and ATP.

In second substrate level phosphorylation, there is the dephosphorylation of phosphoenol pyruvate by pyruvate kinase enzyme and the products are pyruvate and ATP.

In mitochondria, ATP can be generated by the help of substrate level of phosphorylation through succinyl Co-A.

Enzyme ceratine phosphokinase is useful for the conversion of the phosphate from phosphoceratine to ADP to ATP in the brain and the muscles.

So, from above explanation, it is clear that the option b is correct.

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