Lipogenesis, or fatty acid synthesis, occurs in several cycles. A diagram of the

Question

Lipogenesis, or fatty acid synthesis, occurs in several cycles. A diagram of the reactions of the first cycle or fatty acid synthesis is shown below. Which of the following statements are true? Select all the true statements. Malonyl CoA adds a two-carbon group to the growing fatty acid chain with each cycle. The reactions of lipogenesis include, but are not limited to, two reductions and a dehydration. Acetyl-SCoA is used to produce malonyl-SCoA. Growing fatty acid chain is bound to an acyl carrier protein (ACP). The first cycle of lipogenesis yields CO2, 1 NADP^+, and an acyl group attached to ACP. Each cycle lengthens the fatty acid chain by three carbon atoms.

Explanation / Answer

1. Malonyl CoA adds two carbon group to the growing fatty acid chain with each cycle ---------> TRUE

2. The reactions of lipogenesis include, but are not limited to, condensation, reduction, and dehydration. -------> TRUE

3. Acetyl-SCoA is used to produce malonyl-SCoA ---> TRUE

4. The growing fatty acid is bound to an acyl carrier protein (ACP) ---> TRUE

5. The first cycle of lipogenesis yields CO2, 1 NADP+, and an acyl group attach to ACP ----> FALSE (The first cycle of lipogenesis yields CO2, 2 NADP+, and an acyl group attach to ACP).

6. Each cycle of lipogenesis lengthens the fatty acid chain by three carbon atoms. -----> FALSE (Each cycle of lipogenesis lengthens the fatty acid chain by two carbon atoms)

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