What does clonal expansion explain? A. How Her2 genes are amplified in certain m

Question

What does clonal expansion explain?

A. How Her2 genes are amplified in certain metastatic breast cancer cells.

B. How 3T3 cells form foci derived from a single transformed cell.

C. How a single human oncogene transforms mouse 3T3 cells.

D. How His+ Salmonella cells are generated after exposure to a mutagen in the Ames test.

E. How precancerous cells within a given lineage progressively undergo sequential adaptive mutations that confer increased proliferative capacity & survivability over time.

Explanation / Answer

A. How Her2 genes are amplified in certain metastatic breast cancer cells.

Metastasis in cancer cells can be explained by clonal expansion, which as a sign if natural selection in cancer cells.

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