Your friend is trying to understand how the hormone cortisol affects kidney, liv
ID: 7089 • Letter: Y
Question
Your friend is trying to understand how the hormone cortisol affects kidney, liver, and bone cells by examining a set of cell lines derived from kidney cells, liver cells, and bone cells. She gets the following result when she examines her cell lines for expression of the cortisol receptor on a Western blot depicted in panel A of the figure below.
Unfortunately, after she performs this experiment, she mixes up her cell lines and is not sure which line comes from which cells. She labels the cell lines A, B, and C and then examines the activity of a cortisol-responsive reporter gene’s expression in the presence and absence of cortisol and collects the data depicted in panel B of the figure below.
A. Which cell line do you think is the bone cell line? Explain.
B. Provide a possible explanation for why cell line B and cell line C could show differences in their cortisol response
Explanation / Answer
Could you post your question again as the data from the experiment is missing
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