2. For at least three different classes of lipids (choose from the triacylglycer

Question

2. For at least three different classes of lipids (choose from the triacylglycerols, glycerophospholipids, steroid hormones, bile acids or gangliosides) give the function of that class of lipid, identify whether the class of lipids is considered weakly or strongly amphiphilic and explain how that degree of amphiphilicity is important to the function of that class of lipids. Answer within the table shown below these need to be full (extentive) explanations.

insert labeled and fully hand-drawn figure here) 2. For at least three different classes of lipids (choose from triacylglycerols, glycerophospholipids, steroid hormones, bile acids or gangliosides ) give the function of that class of lipid, identify whether the class of lipids is considered weakly or strongly amphiphilic and explain how that degree of amphiphilicity is important to the function of that class of lipids. Answer within the table shown below. These need to be full (extensive) explanations. (9 pts) Class of lipids How is the degree of Function(s) of that class of lipid (1 pt each) Weakly or strongly amphiphilic or amphipathic amphipathicity with explanation based on (amphiphilicity) important structure of the lipid (1 pt to the function of the class each) of lipid? (1 pt each) type answer here) type answer here type answer here! type answer type answer here] type answer here] itype answer here] type answer here] type answer here] type answer herej type answer here] type answer here

Explanation / Answer

Glycerophospholipids

(GPL)

Example : Phosphotidylethanol amines, phosphotidylcholines

Mainly helps in regulation of many cellular process and they are structural components of biological membranes

2) They helps in modulating the cellular responses through internal and external communication

1) High amphiphilicity nature helps in the formation of lipid bilayer structures of membranes

2) High amphiphathic nature involves in major important functions like glycerophospholipids act as as surfactant in the lung and as precursor of secondary messengers.

Triacylglycerol/triglycerides

Examples : Palmitic acid, oleic acid, stearic acid  

Due to weak or no amphilic nature i.e hydrophobic nature of triglycerol, they dont need hydration thus it saves the energy required to carry out the water also.

2) Hydrophobic nature also helps the skin to act as insulator

Bile acids

Examples : Deoxycholic acid, lithocholic acid

1) They mainly helps in the digestion and absorption of fats/fat soluble vitamins in the small intestine

2) Helps in chloesterol homeostasis

Amphiphilic nature of bile acids helps in

1) Emulsification of lipid aggregates : Bile acids act as detergent molecules and form micelles which fat globule molecules break down or emulsify into small minute, microscopic droplets

2) Solubilization and transport of lipids in an aqeous environment : Bile acids act as lipid carriers and solubilise all the fat molecules by forming miscelles which suspend in water.

Class of lipids Function of that class of lipid weakly/strongly amphilic/amphipathic How degree of amphiphilicity/amphipathitcity

Glycerophospholipids

(GPL)

Example : Phosphotidylethanol amines, phosphotidylcholines

Mainly helps in regulation of many cellular process and they are structural components of biological membranes

2) They helps in modulating the cellular responses through internal and external communication

Highly amphiphilic i.e both hydrophilic nature (phosphate ester position) and hydrophobic nature (fatty acid)

1) High amphiphilicity nature helps in the formation of lipid bilayer structures of membranes

2) High amphiphathic nature involves in major important functions like glycerophospholipids act as as surfactant in the lung and as precursor of secondary messengers.

Triacylglycerol/triglycerides

Examples : Palmitic acid, oleic acid, stearic acid  

They mainly involves in the storage of energy for future use. They are observed in adipocytes of adipose tissue. weakly amphiphilic or amphiphilic i.e only hydrophobic in nature (fatty acids)

Due to weak or no amphilic nature i.e hydrophobic nature of triglycerol, they dont need hydration thus it saves the energy required to carry out the water also.

2) Hydrophobic nature also helps the skin to act as insulator

Bile acids

Examples : Deoxycholic acid, lithocholic acid

1) They mainly helps in the digestion and absorption of fats/fat soluble vitamins in the small intestine

2) Helps in chloesterol homeostasis

Strong amphiphilic lipid i.e both hydrophilic nature (carboxylic side chain) and hydrophobic nature (methyl groups)

Amphiphilic nature of bile acids helps in

1) Emulsification of lipid aggregates : Bile acids act as detergent molecules and form micelles which fat globule molecules break down or emulsify into small minute, microscopic droplets

2) Solubilization and transport of lipids in an aqeous environment : Bile acids act as lipid carriers and solubilise all the fat molecules by forming miscelles which suspend in water.

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