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6. The experiment of Avery, MacLeod, and McCarty in which virulent by transforma

ID: 696936 • Letter: 6

Question

6. The experiment of Avery, MacLeod, and McCarty in which virulent by transformation was significant because it showed that nonvirulent bacteria were made A) bacteria can undergo transformation. B) genes are composed of DNA only. are more susceptible to pneumonia than are humans. D) pneumonia can be cured by transformation. E) virulence is determine genetically 7. An Okazaki fragment is a A) fragment of DNA resulting from endonuclease action. B) fragment of RNA that is a subunit of the 30S ribosome. C) piece of DNA that is synthesized in the 3' 5' direction. D) segment of DNA that is an intermediate in the synthesis of the lagging strand E) segment of RNA synthesized by primase to initiate DNA synthase. 8. A certain bacterial mRNA is known to represent only one gene and to contain about 800 nucleotides. If you assume that the average amino acid residue contributes 110 to the peptide molecular weight, the largest polypeptide that this mRNA could code for would have a molecular weight of about: A) 800 B) 5,000. C) 30,000 D) 80,000 E) An upper limit cannot be determined from the data given. 9. Which one of the following is true about the genetic code? All codons recognized by a given tRNA encode different amino acids. A) B) It is absolutely identical in all living things. C) Several different codons may encode the same amino acid D) The base in the middle position of the tRNA anticodon sometimes permits 'wobble base pairing with two or three different codons E) The first position of the tRNA anticodon is always adenosine. 10. Aminoacyl-tRNA synthetases (amino acid activating enzymes) A) recognize specific tRNA molecules and specific amino acids B) in conjunction with another enzyme attach the amino acid to the tRNA. C) interact directly with free ribosomes. D) occur in multiple forms for each amino acid. E) require GTP to activate the amino acid. 11. Fluid Mosaic model of membrane defines membranes to be fluid in nature. Which of the following does not increase the fluidity of the billayer membrane. A. An increase in unsaturated fatty acid content in the phospholipids B. Removal of cholesterol molecules that are embedded in bilayer C. An overall increase cis-fatty acid content in phospholipid bilayer. D. Transition from cis to trans-fatty acid content in the phospholipid bilayer. E. An overall decrease in carbon chain length of the fatty acids in bilayer.

Explanation / Answer

6. B) genes are composed of DNA only.

Avery, MacLeod, and McCarty performed experiments to determine the chemical nature of the transforming principle. His experiment strongly implied that DNA is the transforming factor and not proteins and showed that genes are made of DNA.

7. C) piece of DNA that is synthesized in the 3’ -> 5' direction.

Okazaki fragments are short, newly synthesized DNA fragments that are formed on the lagging template strand during DNA replication. DNA is synthesized from 5' to 3', so when copying the 3' to 5' strand, replication is continuous. To synthesize the lagging strand (the 3' to 5' strand) synthesis must occur in small sections .These new stretches of DNA are called Okazaki fragments.

8. C) 30,000

A certain bacterial mRNA is known to represent

One gene contains about 800 nucleotides. Assume that the average amino acid residue contributes 110 to the peptide molecular weight. Number of amino acids = 266 the largest polypeptide that this mRNA could code for would have a molecular weight of about: 30,000

9.C) several different codons may encode the same amino acid

10.A) recognize specific tRNA molecules and specific amino acids.

Aminoacyl-tRNA synthetases are amino acid–specific. There is at least one enzyme specific for each amino acid.

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