QUESTION 1 From the microarrays video: what is the whole purpose of this techniq

Question

QUESTION 1 From the microarrays video: what is the whole purpose of this technique?

a. To scan the genome for mutations in the offpring. b. To identify the father of the offpring. c. To identify specific SNPs in each homologous chromosome. d. To identify over-represented genes. r

QUESTION 2 A paternity test was performed and three potential fathers were tested. As explained in the animation, all DNAs were digested and run on a gel. The different DNA fragments obtained for each individual are listed below. What can you conclude?

Individual Band sizes (bp) Mother 1000, 700, 500, 450, 300 and 200 Offpring 1000, 800, 650, 500, 300 and 150 Father #1 800, 700, 650, 550, 350 and 200 Father #2 1000, 900, 700, 400, 200 and 150 Father #3 900, 800, 650, 400, 350 and 150

a. Father #1 is the real father b. Father #2 is the real father c. Father #3 is the real father d. None of these individuals can be the father

QUESTION 3 Which statement(s) is(are) not true about GWAS?

a. GWAS scan the entire genome for QTLs b. Like QTL mapping, GWAS use introgression lines. c. GWAS are used to calculate the distance in cM of two genes involved in the same disease. d. A and B e. B and C f. A, B and C

QUESTION 4 GWAS take advantage of linkage disequilibrium since for some markers there is a higher frequency association between marker and a particular QTL.

True False

Explanation / Answer

Ans 1....

Overall purpose of microarrays technique:- is a) to scan genome for mutations in the offspring.

In microarrays, an array of protein / DNA samples is taken, and complementary sample of protein/DNA is added to each of the wells. The well showing un-hybridized samples is considered as a positive test for mutant.

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