Please answer and explain the following question: Which of the following stateme

Question

Please answer and explain the following question:

Which of the following statements about vesicular membrane fusion is fals Membrane fusion does not always immediately follow vesicle docking. The hydrophilic surfaces of membranes have water molecules associated with them that must be displaced before vesicle fusion can occur. The GTP hydrolysis of the Rab proteins provides the energy for membrane fusion. The interactions of the v-SNAREs and the t-SNAREs pull the vesicle membrane and the target organelle membrane together so that their lipids can intermix.

Explanation / Answer

Answer.

c. The GTP hydrolysis of the Rab proteins provides the energy for membrane fusion.

GTP hydrolysis on Rab, providing energy for v-t snare interaction, gets into GDP-bound conformation and gets off of membrane (Rab has geranyl-geranyl anchor, one of isoprene anchors)

Rab proteins are important components of fusion process, and main role is to allow v-t snare cognate pair interaction and recognition; proof-read.

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