Which of the following statements about extracellular antigens is false? a. They

Question

Which of the following statements about extracellular antigens is false?

a. They may possess several epitopes.

b. They may interact with several different antibody paratopes.

c. They may be presented to several different TH cells.

d. They may be presented to several different Tc cells.

Immunization with the bovine vaccinia virus confers protection against human smallpox. What can you therefore conclude?

a. The two viruses share common epitopes.

b. Both viruses are recognized by common TCRs.

c. Both viruses are recognized by common BCRs.

d. All of these conclusions are possible.

Explanation / Answer

Extracellular antigens include bacteria, antigens of tumour cells, viral infected cells, etc.

a. They may possess several epitopes. ----------> TRUE (epitopes are the antigen determining sites, which may be huge in number)

b. They may interact with several different antibody paratopes. ------------> TRUE (Paratope is the antigen binding site of antibody).

c. They may be presented to several different TH cells. -----------> TRUE

d. They may be presented to several different Tc cells. ----------> FALSE (Extracellular antigens are presented to helper T cells, and cytotoxic T cells are specific towards antigens)

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