There are three possible bristle phenotypes on the leg of a certain insect speci

Question

There are three possible bristle phenotypes on the leg of a certain insect species: 1. wild-type phenotype is a single row of bristles. 2. some mutants have no bristles. 3. other mutants have two rows of bristles. The development of these bristles is controlled by a linear pathway involving the molecules A, B, C, and D, which are encoded by genes A, B, C, and D, respectively. The order of action of the molecules A, B, C, and D during bristle formation is unknown. Mutant alleles a and b result in missing bristles (M), while the mutant alleles c and d result in an extra row of bristles (E). The table shows all possible combinations of phenotypes in double mutants. Analyze the results, and decide the order of action of the A,B, C, and D molecules in bristle formation.

c d

E M a

M M b

Explanation / Answer

The bristle formation in the insect species followed epistatic phenomenon.

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