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1) which of the following would indicate that a disease has a genetic, rather th

ID: 68334 • Letter: 1

Question

1) which of the following would indicate that a disease has a genetic, rather than environmental, cause?

a) the disease has a specific age of onset   

b) a high level of concordance among monozygotic twins  

c) the disease does not occur in individuals that are exposed to a similar environment  

d) the disease is similar to a known genetic disease in an animal such as a mouse   

e) all of these are correct

2) Which of the following prior conformations may reslt in a prion-related infection?

a) PrPSc

b) PrPC

c) both can cause disease

3) which of the following is not a prior related disease?

a) Phenylketonuria

b) Creutzfeldt-Jacob disease

c) Gerstmann-Straussler-Scheinker disease

d) Familial fatal Insomnia

e) All of these are correct

Explanation / Answer

1. All of these are correct. - Because all the above said statements are true for a genetic disorder.

2. PrPSc - It is the infectitious form of PrPC protein.

3. Phenylketonuria - It is inborn error in the metabolism of phenylalanine. It is not a prion related disease.