Valinomycin, a substance which transports K+ ions across lipidbilayers and down

Question

Valinomycin, a substance which transports K+ ions across lipidbilayers and down their concentation gradient, kills cells. Whichof the following is the cause of cell death?

Elevated concentrations of K+ ions inside a cell are toxic.

A K+ ion concentration gradient is essential for secondaryactive transport.

Dissipating the K+ ion concentration gradient results inuncontrolled ATP hydrolysis.

The Na+K+ ATPase cannot work in the absence of a K+ ionconcentration gradient.

Elevated concentrations of K+ ions inside a cell are toxic.

Explanation / Answer

Valinomycin is highly selective to K+, the formation ofcomplex cause the uncouple of oxidative phosphorylation. Thus, the answer should be The Dissipating the K+ ion concentrationgradient results in uncontrolled ATP hydrolysis.

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