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Double-stranded DNA breaks that are repaired using RAD51, an 3\' 5\' exonuclease

ID: 67477 • Letter: D

Question

Double-stranded DNA breaks that are repaired using RAD51, an 3' 5' exonuclease and strand invasion of the broken end of the DNA into an intact double-helix is termed Photoreactivation repair Nonhomologous end-joining Homology-directed recombination Excision repair MUT repair How does a transposable element differ from the phage? It cannot cross into the host DNA It can cross into the host DNA It has no specific site where it must insert into the host DNA It has no genes in it None of these is correct; a transposable element is a form of phage Transposons can cause Deletions and inversions only Inversions and translocations only Translocations and altered ORFs only Deletions, inversions and translocations only Deletions, inversions, translocations and altered ORFs LINES and SINES, are classes of transposons, that Cannot transpose and so are of no consequence to humans Are only found in 1 to 3 copies in the human genome Undergo conservative transposition Have long terminal repeats Are believed to transpose through RNA intermediates

Explanation / Answer

43) A transposable element (TE or transposon) is a DNA sequence that can . on or off due to certain environmental conditions or during different stages of cell .... Mu phage transposition is the best known example of replicative transposition.

44) Although the physiological ion is Mg2+, the transposase can also use the cofactor Mn2+, which seems to cause a relaxation in target site specificity.

45) Transposons in maize; Transposons in Drosophila; Transposons in Bacteria; Retrotransposons; HIV-1; LINES (Long interspersed elements); SINES (Short ... She found that they were responsible for a variety of types of gene mutations,

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