1. The mRNA for the Alzheimer-related gene is 2400 nucleotides long when isolate

Question

1. The mRNA for the Alzheimer-related gene is 2400 nucleotides long when isolated from neurons, but 2900 nucleotides long when isolated from glial cells. Genomic DNAs isolated from the two cell types show the identical nuclotide sequence. Which of the following mechanisms best accounts for the difference in the sizes of the mRNAs?

A) Site-specific recombination

B) Transprostion

C) Alternative splicing

D) Post-translational modification

E) Variations in terminal glycosylation

2. How can a single gene encode for more than one protein?

A) by mutating their genes

B) by removing some exons during splicing

C) by transcribing multiple copies of mRNA

D) by using different codons

E) by using transgenes

Thank you for answering. Would you please expain why?

Explanation / Answer

Q1). C) Alternative splicing

Q2). B) by removing some exons during splicing

Alternative splicing is a regulated process during gene expression that results in a single gene coding for multiple proteins. In this process, particular exons of a gene may be included within or excluded from the final, processed messenger RNA (mRNA) produced from that gene.

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