1. An effective respiratory carrier protein must be able to pick up oxygen from

Question

1. An effective respiratory carrier protein must be able to pick up oxygen from the lungs and deliver it to the peripheral tissues. Two oxygen dissociation curves for proteins A and B are shown below. Explain whether or not each of these is an effective carrier. If your answer is “neither one”, show on the same figure, where the curve for an effective carrier would be. Data: pO2 = 100 torr in the lungs and 20 torr in the tissues.

2. If a substrate were to have equal affinities for the T and R forms of an allosteric enzyme, what would happen to the kinetics of this enzyme? In addition to explaining in words, also show your answer graphically.

3. Predict whether each of the following conditions will increase or decrease the tendency of HbS molecules to polymerize in vitro. Give your rationale for each answer. (a) Increase in temperature (b) Increase in partial pressure of oxygen (c) Removing 2,3-BPG from the HbS molecule (d) Increase in pH

Explanation / Answer

We are supposed to answer only one question per post.

The curve shape is correct. But both the curves need to be a little to the left of the graph. towards the y axis.

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