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This is some homework for my Cell and Molecular Biology class. Any help would be

ID: 66089 • Letter: T

Question

This is some homework for my Cell and Molecular Biology class. Any help would be much appreciated!

2. (1 point) Figure below shows the organization of a protein that normally resides in the plasma membrane. The boxes labeled 1 and 2 represent membrane-spanning sequences and the arrow represents a site of action of signal peptidase. Given this diagram, which of the following statements must be true?

Hint; Draw this protein within the translocon (see figure 15-16 on slide 52). Now, which way would the protein be incorporated into a vesicle?

(a)        The N-terminus of this protein is cytoplasmic.

(b)       The C-terminus of this protein is cytoplasmic.

(c)        The mature version of this protein will span the membrane twice, with both the N and C-termini in the cytoplasm.

(d)       None of the above.

Explanation / Answer

(b)       The C-terminus of this protein is cytoplasmic.

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