Adrenaline stimulates glycogen breakdown in skeletal muscle cells by ultimately

Question

Adrenaline stimulates glycogen breakdown in skeletal muscle cells by ultimately activating glycogen phosphoiylase, the enzyme that breaks down glycogen, as depicted the figure below. Which of the following statements below is false? Explain your answer. A constitutively active mutant form of PKA in skeletal muscle cells would lead to a decrease in the amount of unphosphorylated phosphorylase kinase. A constitutively active mutant form of PK A in skeletal musele cells would not increase the affinity of adrenaline for the adrenergic receptor. A constitutively active mutant form of PKA in skeletal muscle cells would lead to an excess in the amount of glucose available. A constitutively active mutant form of PKA in skeletal muscle cells would lead to an excess in the amount of glycogen available.

Explanation / Answer

D). A constitutively active mutant form of PKA in skeletal muscle cells would lead to an excess in the amount of glycogen available.

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