Which of the following statements about mutations in population genetics is true

Question

Which of the following statements about mutations in population genetics is true?

1/ Mutation frequencies can be calculated from the frequency of the homozygous recessive genotypic class alone. 2/ The mutation rate is equal to the allelic frequency of the recessive allele divided by the initial frequency of the recessive allele. 3/ Except in situations of Hardy-Weinberg equilibrium, mutation plays a significant role in changing allelic frequencies. 4/ Mutation is a major force in generating genetic variability, but by itself plays a relatively insignificant role in changing allelic frequencies.

Explanation / Answer

In a population mutation is the source of genetic variability but change in allele frequencies in a population depend on various factors like migration, nonrandom mating genetic drift etc. Hence, option 4 is correct.

Mutation frequency depends both on dominant and recessive allele frequencies. The mutation rate in a population depends on the recessive allele frequency. Changing of allele frequencies depend on several factors but not only mutation.

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