Print CalculatorPeriodic Table - Question 19 of 22 I Map sapling learning Identi

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Print CalculatorPeriodic Table - Question 19 of 22 I Map sapling learning Identify the correct statements about calmodulin. Calmodulin Binding of Ca changes the conformation of calmodulin. Calmodulin contains two Ca2+ binding sites. The loop of the EF hand contains at least one Asp or Glu residue. Each EF hand in calmodulin is formed from a helix-loop-helix motif. calmodulin contains a central flexible sheet that enables the protein to wrap around another protein, regulating its activity. Calmodulin is a structural subunit of proteins such as CaM kinase II. The metal ion in the EF hand of calmodulin is coordinated to seven oxygen atoms Previous Give Up & View Solution O check Answer (0 NextExit- Hint

Explanation / Answer

Calmodulin(CAM) is a calcium binding messenger protein seen in eukaryotes.

The binding of calcium ions to calmodulin induces conformational changes in calmodulin that enables to bind to specific proteins to perform special responce in the cell such as metabolism, immune responce, inflammation. smooth muscle contraction.

Calmodulin can bind to four calcium ions. It is dumbell shaped protein contain N-terminal site and C-terminal sites. Two calcium ions bind to N-terminal site and two calcium inons bind to C-terminal site.

The loop of EF hand contain atleast one Asp or Glu residues

Each EF hand in calmodulin is formed by helix-loop-helix form that contain 4 helix orthogonal bundles.

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