You want to design a cancer killing virus that specifically detect cancer cells
ID: 64537 • Letter: Y
Question
You want to design a cancer killing virus that specifically detect cancer cells miRNA profile and produces a toxin gene call Bax, which is express by CMV promoter. You will develop a miRNA classifier, similar to the one discussed in class to accomplish you goal. You know that the cancer cells very specifically INHIBIT miRNA-1 and miRNA-2.
A}Based on this information alone, draw a genetic circuit that can recognize the cancer cells. Draw and label the promoter, the Bax gene and miRNA binding site.
B}You later realize that miRNA-1 and miRNA-2 is not sufficient to specify cancer cells. You find out that cancer cells also over express specifically miRNA-3 and miRNA-4. Draw a genetic circuit that can sense miRNA-1, miRNA-2, miRNA 3, and miRNA-4 to classify cancer cells. Draw and label the promoter, the Bax gene and miRNA binding site and other transcription unit necessary.
Explanation / Answer
A)
Micro RNAs (miRNA) are the small non-coding RNA that negatively regulates gene expression.
B)
Related Questions
drjack9650@gmail.com
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.