Let\'s imagine that the conversion of substance A to substance D is crucial for
ID: 64481 • Letter: L
Question
Let's imagine that the conversion of substance A to substance D is crucial for proper function of aliens from the planet Rigel VII (illustrated above). As is usually the case, this conversion takes place in a multi-step metabolic pathway as illustrated below. An enzyme represented by the numbered squares catalyzes each of these reactions. The aliens from Rigel VII are plotting the overthrow of the Earth. Being a student in an introductory biology course, you have been selected to protect the world and stop the invasion. Using your understanding of the metabolic pathway above, outline your plan to save the world. Be specific. You can't just say you are going to stop the pathway. Tell me precisely how you plan to prevent the formation of the all-important substance D. (3 points)Explanation / Answer
* One of the enzymes can be evaluated for its structural and functional properties. Using homology modeling and bioinformatics tools, suitable inhibitor that competetively inhibits one of the enzymes, or more precisely, enzyme 3, can be desgined. It would be better if the inhibitor is a volatile compound that can be easily used to target the metabolic pathway. The inhibitors can then be applied on the aliens to inhibit their vital metabolic pathway.
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