1. At the end of mitosis, the activity of Mitosis Promoting Factor (MPF) is turn
ID: 64240 • Letter: 1
Question
1. At the end of mitosis, the activity of Mitosis Promoting Factor (MPF) is turned off. This happens when ___________.
A.
cyclin B is degraded
B.
MPF is exported out of the cell
C.
cyclin dependent kinase is degraded
2. Which of the following is true about DNA Polymerase III?
A.
It moves along the chromosome in the opposite direction as helicase
B.
It is involved in the steps related to replication elongation
C.
It reads a daughter DNA strand to create a new template DNA strand
3. Assume that a bacterial cell had a defective copy of DNA Polymerase I. At which stage would DNA replication be blocked?
A.
All of the RNA would be removed, but no ligation would take place
B.
DNA replication would be completed normally
C.
Both strands of DNA would be copied, but there would be many Okazaki fragments
4. Which of the following would increase the rate of DNA single base mutations, (aka point mutations) but allow DNA synthesis to occur?
A.
Loss of the 3’ to 5’ exonuclease activity from DNA polymerase III
B.
Removal of the 3’ OH from nucleotides
C.
Defects in DNA ligase
A.
cyclin B is degraded
B.
MPF is exported out of the cell
C.
cyclin dependent kinase is degraded
Explanation / Answer
1. A. cyclin B is degraded
Mitosis Promoting Factor (MPF) is composed of two regulatory proteins namely cyclin and cyclin dependent kinases. At the end of mitosis, cyclin dependent kinases remain unchanged and the cyckin B is degraded.
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