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4. Thought experiment: IGNORING issues of molecular recognition, you take the DN

ID: 6405 • Letter: 4

Question

4. Thought experiment: IGNORING issues of molecular recognition, you take
the DNA encoding an exon-intron-exon sequence, DEnature it and put it in with splicing
machinery - would it splice?
a. Yes, because all the sequences in the RNA are also in the DNA.
b. No, because DNA contains deoxyribose while RNA contains ribose.
c. No, because DNA contains Thymine while RNA contains Uracil.
d. No, because DNA is usually double stranded while RNA is usually single
stranded.

5. The following RNA is broken up into its codons by dots:
5’-ATG.GCC.CTA.GCC.ACC.TAA-3’
Which of the following RNA sequences represents a frameshift of this?
a. 5’-ATG.GCC.CTA.GCC.ACC.TAA-3’
b. 3’-ATG.GCC.CTA.GCC.ACC.TAA-5’
c. 5’-A.TGG.CCC.TAG.CCA.CCT.AA-3’
d. 3’-AT.GGC.CCT.AGC.CAC.CTA.A-5’
e. 5’-AAT.CCA.CCG.ATC.CCG.GTA-3’
f. 1,2 and 3
g. 1,3 and 4
h. 2 and 3
i. 1 and 3

6. All tRNA’s except the initiator tRNA pass through all three sites on the
ribosome. Which site does the initiator tRNA skip?
a. E
b. P
c. A
d. Termination

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Explanation / Answer

d f d

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