From the list below, select all statements accurate with respect to hormonal reg

Question

From the list below, select all statements accurate with respect to hormonal regulation of steroid hormone production in males and females.

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hypothalamic secretion of GnRH stimulates LH and FSH secretion in the anterior pituitary

FSH secretion in the anterior pituitary stimulates testosterone secretion in theca cells and Leydig cells

FSH secretion in the anterior pituitary stimulates inhibin secretion by granulosa cells and Sertoli cells of the ovary and testis, respectively

LH secretion stimulates testosterone secretion in both ovarian granulosa and theca cells

LH secretion stimulates testosterone secretion in Leydig and theca cells of the testes and ovaries, respectively

inhibin feeds back to turn down both LH and FSH secretion in the anterior pituitary

inhibin feeds back to selectively suppress LH secretion in the anterior pituitary without changing FSH secretion

inhibin feeds back to selectively suppress FSH secretion in the anterior piutitary without changing LH secretion

testosterone secretion in males always feeds back to inhibit GnRH secretion from the hypothalamus

testosterone secretion in males always feeds back to inhibit anterior pituitary responsiveness to GnRH

progesterone in high concentration has an inhibitory effect on GnRH secretion in the hypothalamus

similar to testosterone's effect in males, estrogen in females always feeds back to inhibit GnRH secretion from the hypothalamus

when estrogen levels in females are low, estrogen feeds back at the hypothalamus to inihibit GnRH secretion from the hypothalamus similar to testosterone's effects in males

when estrogen levels in females are high and unaccompanied by high progesterone levels, estrogen is stimulatory, rather than inhibitory to GnRH secretion in the hypothalamus

if estrogen levels in females are high but are accompanied by high progesterone levels, the powerful inhibitory effects of progesterone override the stimulatory effects of estrogen and suppress GnRH secretion from the hypothalamus

A)

hypothalamic secretion of GnRH stimulates LH and FSH secretion in the anterior pituitary

B)

FSH secretion in the anterior pituitary stimulates testosterone secretion in theca cells and Leydig cells

C)

FSH secretion in the anterior pituitary stimulates inhibin secretion by granulosa cells and Sertoli cells of the ovary and testis, respectively

D)

LH secretion stimulates testosterone secretion in both ovarian granulosa and theca cells

E)

LH secretion stimulates testosterone secretion in Leydig and theca cells of the testes and ovaries, respectively

F)

inhibin feeds back to turn down both LH and FSH secretion in the anterior pituitary

G)

inhibin feeds back to selectively suppress LH secretion in the anterior pituitary without changing FSH secretion

H)

inhibin feeds back to selectively suppress FSH secretion in the anterior piutitary without changing LH secretion

I)

testosterone secretion in males always feeds back to inhibit GnRH secretion from the hypothalamus

J)

testosterone secretion in males always feeds back to inhibit anterior pituitary responsiveness to GnRH

K)

progesterone in high concentration has an inhibitory effect on GnRH secretion in the hypothalamus

L)

similar to testosterone's effect in males, estrogen in females always feeds back to inhibit GnRH secretion from the hypothalamus

M)

when estrogen levels in females are low, estrogen feeds back at the hypothalamus to inihibit GnRH secretion from the hypothalamus similar to testosterone's effects in males

N)

when estrogen levels in females are high and unaccompanied by high progesterone levels, estrogen is stimulatory, rather than inhibitory to GnRH secretion in the hypothalamus

O)

if estrogen levels in females are high but are accompanied by high progesterone levels, the powerful inhibitory effects of progesterone override the stimulatory effects of estrogen and suppress GnRH secretion from the hypothalamus

Explanation / Answer

A) hypothalamic secretion of GnRH stimulates LH and FSH secretion in the anterior pituitary. ----> TRUE

B) FSH secretion in the anterior pituitary stimulates testosterone secretion in theca cells and Leydig cells ----> FALSE (LH secretion in the anterior pituitary stimulates testosterone secretion in theca cells and Leydig cells)

C). FSH secretion in the anterior pituitary stimulates inhibin secretion by granulosa cells and Sertoli cells of the ovary and testis, respectively --> TRUE

D). LH secretion stimulates testosterone secretion in both ovarian granulosa and theca cells ----------> FALSE (LH secretion stimulates testosterone secretion in ovarian theca cells only, and also from testicular leydig cells).

E). LH secretion stimulates testosterone secretion in Leydig and theca cells of the testes and ovaries, respectively -------> TRUE.

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