How would you design a genetic screen to find genes involved in meiosis? A) Gene

Question

How would you design a genetic screen to find genes involved in meiosis?

A) Genes involved in meiosis can be found by screening E.coli mutants that are unable to conjugate in inductional conditions.

B) Genes involved in meiosis can be found by screening mutant Drosophila germ cells from which sterile flies develop after fertilization.

C) Genes involved in meiosis can be found by screening mutant Arabidopsis stem cells from which sterile plants develop on cloning medium.

D) Genes involved in meiosis can be found by screening diploid yeast mutants that are unable to produce viable ascospores on sporulation medium.

Explanation / Answer

Genetic screening is the technique that is used to determine the occurrence of a specific gene in the organism.

The highly regulated developmental program in yeast is sporulation where in diploid cells produce haploid gametes. To determine the genetic pathway that is regulating sporulation can be determined by using screening method. The deletion of gene reduces sporulation in yeast. Thus, the genes involved in meiosis can be found by screening diploid yeast mutants that are unable to produce viable ascospores on sporulation medium.

Hence, the correct option among the following is D.

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