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Bacteria use restriction enzymes to destroy invading, exogenous DNA, for instanc

ID: 63030 • Letter: B

Question

Bacteria use restriction enzymes to destroy invading, exogenous DNA, for instance, DNA injected during bacteriophage infection. How can the restriction enzyme hydrolyze the foreign DNA and not destroy the DNA of the bacterium in which it resides? Bacteria use restriction enzymes to destroy invading, exogenous DNA, for instance, DNA injected during bacteriophage infection. How can the restriction enzyme hydrolyze the foreign DNA and not destroy the DNA of the bacterium in which it resides? Bacteria use restriction enzymes to destroy invading, exogenous DNA, for instance, DNA injected during bacteriophage infection. How can the restriction enzyme hydrolyze the foreign DNA and not destroy the DNA of the bacterium in which it resides?

Explanation / Answer

How can the restriction enzyme hydrolyze the foreign DNA and not destroy the DNA of the bacterium in which it resides?

Restriction enzymes are bound to bacteria to provide defensive mechanism against invading viruses. In bacteria the restriction enzymes selectively cut the foreign DNA in a process called restriction to check their growth and multiplication. While the bacterial DNA is protected by methylation by the enzyme methyltransferase, modifies bacterial DNA and cleavage of its own DNA.

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