Use the pedigree shown below for this question. Square = male, circle = female.

Question

Use the pedigree shown below for this question. Square = male, circle = female. Solid = affected, open = normal/unaffected as per pages 314-317. Assume that the disorder is due to alleles at 1 gene locus and that there are only 2 alleles in this family (A and a; A dominant to a) . The disorder is a lethal “late onset” type; so, affected individuals reach reproductive age before they die of the disorder. Assume that all individuals with genotype ‘aa’ will have the disorder. For each inheritance pattern listed below, identify a parent and their child in the pedigree (one pair only for each inheritance pattern) that would allow you to eliminate that inheritance pattern as a possibility for this pedigree and these data. Use the symbols and identification system from figure 11.18b to identify individuals in the pedigree and in your answer (e.g. individual” I-2” is the affected male in the first generation at the top, right).

_______ __________: X-linked dominant.

_____ ____________: X-linked recessive.

Explanation / Answer

Answer:

1.In the 2nd generation 3 and 4 X-linked dominant

2. In th 3nd generation 3,7 X-linked recessive.

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