How does an enhancer affect the transcription of distant genes? Enhancers can re

Question

How does an enhancer affect the transcription of distant genes? Enhancers can recombine the DNA so that large portions of intervening sequence between the enhancer and promoter can be removed. Enhancers are proteins that diffuse through the nucleus, affecting genes at any location on the chromosomes. Enhancers can affect distant genes because the DNA between the enhancer and the promoter can be looped out. Enhancers cannot affect distant genes but must instead be in close proximity to a promoter. Enhancers can enhance the function of insulator sequences on the DNA, blocking the unwanted transcription. How does an enhancer affect the transcription of distant genes? Enhancers can recombine the DNA so that large portions of intervening sequence between the enhancer and promoter can be removed. Enhancers are proteins that diffuse through the nucleus, affecting genes at any location on the chromosomes. Enhancers can affect distant genes because the DNA between the enhancer and the promoter can be looped out. Enhancers cannot affect distant genes but must instead be in close proximity to a promoter. Enhancers can enhance the function of insulator sequences on the DNA, blocking the unwanted transcription.

Explanation / Answer

Enhancers can affect distant genes because the DNA between the enhancer and the promoter can be looped out.

Enhancers need not be present next to the genes they regulate. They can be present some distance away. When transcription factors bind to the enhancers, they loop to trigger the transcription of specific genes.

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