ips: In autosomal dominant conditions, every afflicted individual has, at least,
ID: 61735 • Letter: I
Question
ips:
In autosomal dominant conditions, every afflicted individual has, at least, one parent with the affliction.
In autosomal recessive conditions, it is possible for afflicted individuals to sometimes have two parents that are both “normal” in phenotype, which would mean both parents are only carriers.
In X-linked recessive conditions, all, or most, afflicted individuals are male. Females of afflicted sons are carriers, and have “normal” phenotypes.
Problem: Pedigree 3
Which selection below is the most probable inheritance basis of the condition being traced in this pedigree?
Autosomal Dominant
Autosomal Recessive
X-linked Recessive
Explanation / Answer
The given pedigree exhibits X - linked recessive trait because all males affected and females producing affected males are carriers.
In X - linked recessive inheritance males are more prone to disease because they carry the disease trait. If the affected offspring’s mother has brother or father containing the same trait then the mother pass the trait to her offspring. The affected males produce unaffected daughters who can produce 50% affected sons. Hemophilia is the example of X - linked recessive trait.
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