Multiple Choice An example of a nonspecific chemical barrier to infection is (1p
ID: 61039 • Letter: M
Question
Multiple Choice
An example of a nonspecific chemical barrier to infection is (1pt)
a-Unbroken skin
b-Lysozyme in saliva
c-Cilia in respiratory tract
d-All of these
Host defenses include both innate, nonspecific components and acquired specific components. Which of the following is/are exclusive to the acquired, specific defenses? (Circle all that apply if more than one) (1pt)
a-Leukocytes
b-Antimicrobial proteins
c-Inflammation
d-Fever
e-Lymphocytes
What is included in GALT? (1pt)
a-Thymus
b-Peyer’s patches
c-Tonsils
d-Breast lymph nodes
Which of the following is a specialized tissue cell similar to basophils that triggers local inflammatory reactions and is responsible for many allergic symptoms? (1pt)
a-Mast cell
b-Macrophage
c-cell
d-killer cell
e-Neutrophil
An example of an exogenous pyrogen is (1pt)
a-Interleukin-1
b-Complement
c-Interferon
d-Endotoxin
Which of the following components has a role in the third line of defense as well as in the second line of defense? (1pt)
a-Fever
b-Complement
c-Lysosome
d-All of the above
Which of the following substances is/are not produced by phagocytes to destroy engulfed microorganisms? (Circle all that apply if more than one) (1pt)
a-Hydroxyl radicals
b-Superoxide dismutase
c-Hydrogen peroxide
d-Bradykinin
Which of the following is the end product of the complement system? (1pt)
a-Properdin
b-Cascade reaction
c-Membrane attack complex
d-Complement factor C9
Short Answer
1-What constitutes the first line of defense? What factors are involved? (1pt)
2-What constitutes the second line of defense? What factors are involved? (1pt)
Explanation / Answer
1. Lysosome in saliva- It is a non specific chemical barrier which breaks the bacterial cell wall
2. Lymphocytes - They are specific for acquired immunity because they produce antibodies against specific antigen
3. Peyer’s patches - It is gut associated lymphod tissue (GALT) found in lower intestine
4. Mast cell - It is very similar to basophil and secretes histamine,heparin and other chemicals involved in inflammation.
5. Endotoxin - It is secreted out hence exogenous
6. All the above - fever, complement and lysosomes all are involved in both second and third line defense
7. Bradykinin - It is not produced by phagocytes.
8. Membrane attack complex is the end product of complement system
9. First line defense is non specific immune response - It aims to prevent entry of microorganism into the body which includes physical barrier skin, non specific chemicals lysozymes etc
10 Second line defense is also non specific - It kills any type of microbe with its phagocytosis or psuedophodia to engulf the microbe.
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