1. Which mode of inheritance results in both alleles being detected equally in t
ID: 60941 • Letter: 1
Question
1. Which mode of inheritance results in both alleles being detected equally in the heterozygous phenotype?
codominance
incomplete dominance
complete dominance
incomplete penetrance
epistasis
2.Which of the following describes the ability of a single gene to have multiple phenotypic effects?
epistasis
incomplete dominance
pleiotropy
multiple alleles
3.Loss-of-function mutations are more likely to be
dominant
recessive
codominant
less penetrant
more penetrant
lethal
4.Which statement(s) is(are) correct?
When determining the penetrance of a condition, the severity of the clinical features is important.
The variation in the type and severity of clinical features of a genetic disorder is called reduced penetrance.
The variation in the type and severity of clinical features of a genetic disorder is called variable expressivity.
Variable expressivity occurs when a single genotype produces multiple distinct phenotypes that affect different functions.
Two of the above are correct.
Three of the above are correct.
a.codominance
b.incomplete dominance
c.complete dominance
d.incomplete penetrance
e.epistasis
Explanation / Answer
1. In codominance both alleles being detected equally though the individual is heterozygous.
Hence, the correct option is (a) codominance.
2. Pleiotropy is the condition in which a single gene can control multiple phenotypic effects.
Hence, the correct option is (c) pleiotropy.
3. Loss of function mutations is more likely to be lethal.
Hence, the correct option is (f) lethal.
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