B. Why is ACh still transported into vesicles at a lower Na+ concentration in th

Question

B. Why is ACh still transported into vesicles at a lower Na+ concentration in the absence of ATP? Explain this in no more than 3 sentences.

C. Does this process act as a uniporter, symporter, or antiporter? In no more than 3 sentences, explain HOW THE DATA given supports your answer.

140 100 80 60 40 20 Acetylcholine Environmental (Na 1001001001010010 AT SX2349 Overlapping error bars indicates an insignificant difference: Low values are tlkely due to background results and do not represent any significant transport of

Explanation / Answer

A. ATP,provides energy for creating the proton gradient across the memberane inorder to transport acetlycholine into vesicle

B . the lower sodium concentration does not show much effect on the actlycholine transport as it maintains the equilibrium acidic PHsurrounding the vesicle , as the memberane depolarises due to increase in the protons gradient ,there by acetlycholine transport into the vesicles takes place .

c. The process act as a antiporter , which is a proton pump there is a efflux of protons along with the sodium influx through the antiport . there sharp change in the bar representation where it moves towards the more positive side . show + 100 + in the first bar of the graph.

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