[5 points] T appears to be the: 3. he most important contribution to the stabili

Question

[5 points] T appears to be the: 3. he most important contribution to the stability of a protein's conformation A) entropy increase from the decrease in odered water molecules forming a solvent shel B) maximum entropy increase from ionic interactions between the ionized amino acids in a C) sum of free energies of formation of many weak interactions among the hundreds of D) sum of free energies of formation of many weak interactions between its polar amino E) stabilizing effect of hydrogen bonding between the carbonyl group of one peptide bond around it. protein amino acids in a protein. acids and surrounding water and the amino group of another 4. [5 points] In the diagram, the plane drawn behind the peptide bond indicates the: H R A) absence of rotation around the C-N bond because of its partial double-bond character B) plane of rotation around the Ca-N bond. C) region of steric hindrance determined by the large C-O group. D) region of the peptide bond that contributes to a Ramachandran plot. E) theoretical space between-180 and +180 degrees that can be occupied by the and angles in the peptide bond.

Explanation / Answer

Ans 3 : E) Stabilizing effect of hydrogen bonding between the carbonyl group of one peptide bond and the amino group of the other.

There are many factors that play a major in the stability of proteins , the most important of them being the hydrogen bond. It occurs between the two electronegative atoms of the different groups and help in stabilising the protein molecule.

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