1.Which of these statements about cAMP is incorrect? a. cAMP is generated by cyc

Question

1.Which of these statements about cAMP is incorrect?

a. cAMP is generated by cyclization of ATP

b. the mechanism of cAMP generation is catalyzed by adenylate cyclase

c. cAMP is an intercellular messenger

d. cAMP can be produced following binding of a hormone to a receptor

e. all of the above are correct

2. Glucagon inhibits glycolysis in the liver because:

   a.   it decreases the activity of Fructose-bisphosphatase 2

   b.   it causes an increase in Fructose-2,6-bisphosphate concentration

   c.   it increases the activity of Phosphofructokinase-2

   d.   it causes a decrease in Fructose-2,6-bisphosphate concentration

   e.   both c and d

Explanation / Answer

1.
cAMP cannot be produced by binding of a hormone to a receptor.
Galpha-s stimulates production of cAMP
hence option d is the answer

2.
Glucagon inhibits kinase part of phosphofructokinase-2 part and activates phosphate part of
phosphofructokinase-2 and degrades Fructose-2,6-bisphosphate concentration
Hence option e is correct

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