These questions are often less obvious that they seem -- I\'m wondering if \"spo

Question

These questions are often less obvious that they seem -- I'm wondering if "spontaneous deaminations" would fit under the category of environmental risk factor, same with C. My gut is no, but I'm wondering if my definition is too narrow.

It has been estimated that about 85% of cancers that develop are environmentally induced (the remaining are inherited to some degree). Which of the following represents an environmental risk factor that could induce cancer?

A. The oxidative damage to DNA caused by radiation (X-rays, gamma rays, radon gas)

B. Spontaneous deaminations and depurinations of the bases in DNA

C. The error rate of DNA polymerase

D. A, B, and C

E. A and B

Explanation / Answer

Yes, you are right. Endogenous factors of damage are different from exogenous factors of damage. Environmental factors are the exogenous factors of damage, and spontaneous deaminations and error rate of DNA polymerase comes under endogenous factors of damage.

Thus, the correct option is, A. The oxidative damage to DNA caused by radiation (X-rays, gamma rays, radon gas)

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