C Below Is A Pathway S x PS2-Fall 2015 B 2 x PS2-Int2015.pdf x Laurie Single Sig

Question

C Below Is A Pathway S x PS2-Fall 2015 B 2 x PS2-Int2015.pdf x Laurie Single Sign x C https:// mylearningspace.Wlu.ca 68105 A My Home BI-226-AB Genetics Joshua Falkenstern 6. In Drosophila, females of wild-type appearance but heterozygous for three autosomal genes are mated to males showing all three autosomal recessive traits: glassy eyes (Ge), coal-colored bodies (Cb) and striped thoraxes (St). One thousand progeny of this cross are distributed in the following phenotypic classes a. Which gene is in the middle? Phenotype Number I+ Cb 450 Ge St 414 b. Draw a genetic map based on this data showing relative locations of the Ge Clb St 44 genes with map distances between them Cbl St 22 Ge 19 4 Ge Cb Total 1000 c. Calculate the interference value for this region DO 40 ENG 9:42 AM US 2015-10-19

Explanation / Answer

a. 'Ge' would be in the middle

b. Cb------->Ge = (45+44+4+2/1000) 100=10.5 m.u

Ge------>St = (22+19+4+2/1000) 100= 4.7 m.u

Cb----> St= 10.5+4.7= 15.2 m.u

Cb----------------(10.5 m.u)----------------Ge----------(4.7 m.u)----------St

<-------------------------------------15.2 m.u--------------------------------------->

c. Interference value is 0.98

Expected double cross over (DCO) = (% recomb. Cb-Ge) (% recomb. Ge-St)
= 0.105 x 0.047 = 0.49%

Coefficient Coincidence (C.C)= 6/0.49x1000= 6/490=0.012244

Now, interference= 1-C.C= 1-0.012= 0.98

  

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