Academic Integrity: tutoring, explanations, and feedback — we don’t complete graded work or submit on a student’s behalf.

TABLE 10-3 Common indicators Transition Acid range (pH) color Yellow 0.05 w 1% i

ID: 584641 • Letter: T

Question

TABLE 10-3 Common indicators Transition Acid range (pH) color Yellow 0.05 w 1% in H2O 0.1 g in 26.2 mL 0.01 M NaOH. Then add -225 mL H20 0.1 g in 21.5 mL 0.01 M NaOH. Then add 225 mL H20. 0.1 g in 26.2 mL 0.01 M NaOH. Then add -225 mL H20 0.1w 1% in H2O 0.01 wt% in H2O 0.1 wt% in H2O 0.1 wt% in H2O 0.1 g in 143 mL. 0.01 M NaOH. Then add -225 mL H20 0.02 g in 60 mL cthanol. Then add 40 mL H2O 0.1 g in 23.6 mL 0.01 M NaOH. Then add -225 mL H20 0.1 g in 18.5 mL 0.01 M NaOH. Then add -225 mL H20 0.1wt% in H2O 0.1wt% in H2O 0.1 g in 16.0 mL 0.01 M NaOH. Then add-225 mL H20 0.1 g in 28.2 mL 0.01 M NaOH. Then add -225 mL H20 0.01 g in 50 mL ethanol. Then add 50 mL H20. See above. 0.1 g in 50 mL ethanol. Then add 50 mL H20. See above. See above. 0.05 g in 50 mL ethanol. Then add 50 mL. H20. 0.04 g in 50 mL cthanol. Then add 50 mL H20. 0.01 wt% in H2O Violet Yellow Yellow Yellow Methyl violet Cresol rood Thymol blue Cresol purple Erythrosine, disodium 2.2-3.6 Mcthyl orange Congo red Ethyl orange Bromocresol green Methyl red 0.0-1.6 0.2-1.8 1.2-2.8 1.2-2.8 Orange Red 3.1-4.4 3.0-5.0 3.4-4.8 3.8-5.4 4.8-6.0 4.8-6.4 5.2-6.8 5.6-7.6 5.0-8.0 6.0-7.6 6.4-8.0 6.8-8.0 7.2-8.8 7.3-8.7 7.6-9.2 8.0-9.6 8.0-9.6 8.3-10.5 10.1-12.0 Yellow Yellow Yellow Bromocresol purple p-Nitrophenol Yellow Yellow Colorless Yellow Bluc Yellow Yellow Bromothymol blue Phenol red Neutral red Cresol red Yellow Yellow Cresol purple Thymol blue Colorless Colorless Yellow Blue Pink Bluc Orange red Alizarin yellow Nitramine 10.8-13.0 Crless Orange-brown 0.1 g in 70 mL ethanol. Then add 30 mL H20. Tropacolin O 11.1-12.7 Yellow 0.1 wt% in H20

Explanation / Answer

1. Titration of sodium salt of phenylalanine with HClO4

a) reaction is shown below

b) pH calculation

when 0 ml HClO4 added

say A- represent the sodium salt of phenyl alanine

salt hydrolyzes

let x amount hydrolyzed

A- + H2O <==> HA + OH-

Kb = 1 x 10^-14/6.31 x 10^-3 = x^2/0.1

x = [OH-] = 3 x 10^-7 M

pOH = -log[OH-] = 6.4

pH = 14 - pOH = 7.6

after 2.5 ml HClO4 addition

initial salt = 0.1 M x 10 ml = 1 mmol

HClO4 added = 0.1 M x 2.5 ml = 0.25 mmol

pH = pKa1 + log(base/acid)

      = 2.20 + log(0.75/0.25) = 2.68

after 5 ml HClO4 addition

initial salt = 0.1 M x 10 ml = 1 mmol

HClO4 added = 0.1 M x 5 ml = 0.5 mmol

half equivalence point

pH = pKa1 = 2.20

after 7.5 ml HClO4 addition

initial salt = 0.1 M x 10 ml = 1 mmol

HClO4 added = 0.1 M x 7.5 ml = 0.75 mmol

pH = pKa + log(base/acid)

      = 2.20 + log(0.25/0.75) = 1.72

after 9 ml HClO4 addition

initial salt = 0.1 M x 10 ml = 1 mmol

HClO4 added = 0.1 M x 9 ml = 0.9 mmol

pH = pKa + log(base/acid)

      = 2.20 + log(0.1/0.9) = 1.24

after 10 ml HClO4 addition

initial salt = 0.1 M x 10 ml = 1 mmol

HClO4 added = 0.1 M x 10 ml = 1 mmol

Ist equivalence point

pH = 1/2(pKa1 + pKa2) = 1/2(2.20 + 9.31) = 5.755

after 11 ml HClO4 addition

initial salt = 0.1 M x 11 ml = 1 mmol

HClO4 added = 0.1 M x 11 ml = 1.1 mmol

neutral amino acid formed = 0.9 mmol

protonated amine of amino acid = 0.1 mmol

pH = 9.31 + log(0.9/0.1) = 10.26

after 15 ml HClO4 addition

initial salt = 0.1 M x 11 ml = 1 mmol

HClO4 added = 0.1 M x 15 ml = 1.5 mmol

Second half-equivalence point

pH = pKa2 = 9.31

after 20 ml HClO4 addition

initial salt = 0.1 M x 11 ml = 1 mmol

HClO4 added = 0.1 M x 20 ml = 2 mmol

second equivalence point

all amine is protonated

[protonated amine] = 1 mmol/30 ml = 0.033 M

amine gives off its proton to water and hydrolyze

say x amount is hydrolyzed

Ka2 = 4.9 x 10^-10 = x^2/0.033

x = [H3O+] = 4.02 x 10^-6 M

pH = -log[H3O+] = 5.39

after 30 ml HClO4 addition

initial salt = 0.1 M x 11 ml = 1 mmol

HClO4 added = 0.1 M x 30 ml = 3.0 M

excess [H+] = 1 mmol/40 ml = 0.025 M

pH = -log(0.025) = 1.60

c) pH at first equivalence point = 5.75

d) pH at IInd equivalence point = 5.39

f) indicator Ist equivalence point = bromocresol green