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In studies of the evolution of amino acid sequences in one lineage of Drosophila

ID: 58449 • Letter: I

Question

In studies of the evolution of amino acid sequences in one lineage of Drosophila species, the following changes have been observed (starting with lysine as the ancestral amino acid).

Using the genetic code table from your textbook, determine a set of triplet codons such that only a single nucleotide substitution for each step (arrow) in the diagram could have produced the observed amino acid changes and enter those codon steps in the spaces below. (Note: each arrow represents one nucleotide change from the base of the arrow to its point, e.g. each codon from steps b, c and d must be one nucleotide different from the codon determined for arginine). Type answers in the form CODON-CODON, e.g. UUC-UAC (just because that will be easier to grade).

7 serine arginine- isoleucine threonine lysine z valine N glutamic acid (glu) glycine

Explanation / Answer

Lysine (AAA)------------ Arginine (AGA)                 --------- Serine (AGT / AGC)

-------- Isoleucine (ATA)

-------- Threonine (ACA)

Lysine (AAA) ----------- Glutamic acid (GAA) -------- Valine (GTA)

-------- Glycine (GGA)

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