1. Which of the following channels would not be expected to generate a change in
ID: 57134 • Letter: 1
Question
1. Which of the following channels would not be expected to generate a change in voltage by movement of its substrate across the membrane where it is found? Then explain why?
An aquaporin, a sodium channel, a calcium channel, or a proton channel.
2. A patient went to the doctor for a general checkup and the doctor asked for several tests. The results of the analysis showed that the patient had extremely high levels of cholesterol in blood, which put him in high risk of having a heart attack. Next, the doctor ordered a second analysis, which confirmed that the LDL receptor was expressed in the plasma membrane of the cells.
Give two different reasons that could explain the high level of cholesterol in blood despite the existence of the LDL receptor in plasma membrane.
Explanation / Answer
Q1)
An Aquaporin
Some cells have aquaporinsAquaporin channels are found in the plasma membrane of some cells, where they facilitate diffusion of water across the membrane. Because water is an uncharged molecule, its movement would not be expected to alter the voltage. For these cells, aquaporin conformation regulates the rate and direction of water diffusion across the membrane.
Q2).
Cholesterol is an essential substance that is produced by the body but is also ingested from animal-derived foods. But high cholesterol has risk factor
Reasons for high cholesterol
.Risks of high cholesterol
· There is a chance of developing coronary heart disease also rises as blood's cholesterol level increases. This can cause pain in chest or arm (angina) during stress or physical activity.
Reduce cholesterol level
· Maintaining the healthy & balanced diet. It's important to keep diet low in fatty food i.e., saturated fat for fruit, vegetables and wholegrain cereals. This will also help to prevent high cholesterol returning.
· The lifestyle changes, such as taking regular exercise and giving up smoking (if smoke), can also make a big difference in helping to lower your cholesterol.
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