Let us assume that a G alpha (s) coupled GPCR is activated by Epinephrine. Let u

Question

Let us assume that a G alpha (s) coupled GPCR is activated by Epinephrine. Let us also assume that the transcription factor CREB is phosphorylated by PKA. What is the effect of removing the regulatory units of PKA on CREB phosphorylation in the absence of Epinephrine?

PKA is inactivated in the absence of Epinephrine and CREB is activated

PKA is activated in the absence of Epinephrine and CREB is activated (since the regulatory subunits normally inhibit PKA activation).

PKA is inactivated in the absence of Epinephrine and CREB is inactivated

PKA is inactivated in the absence of Epinephrine and CREB is activated

PKA is activated in the absence of Epinephrine and CREB is activated (since the regulatory subunits normally inhibit PKA activation).

PKA is inactivated in the absence of Epinephrine and CREB is inactivated

Explanation / Answer

PKA is activated in the absence of Epinephrine and CREB is activated (since the regulatory subunits normally inhibit PKA activation).

Related Questions

Navigate

• Browse (All)
• Browse L
• Subjects

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.