Type I single pass integral membrane proteins: undergo posttranslational translo

Question

Type I single pass integral membrane proteins:

undergo posttranslational translocation, have their N-terminal signal sequence cleaved, and have a stop-transfer anchor sequence

undergo cotranslational translocation, have their N-terminal signal sequence cleaved, and have a stop-transfer anchor sequence

undergo cotranslational translocation, have their C-terminus cleaved, and have a stop-transfer anchor sequence

undergo cotranslational translocation, have no signal sequence, and carry positive charges on the N-terminal side of the anchor

undergo posttranslational translocation, have their N-terminal signal sequence cleaved, and have a stop-transfer anchor sequence

undergo cotranslational translocation, have their N-terminal signal sequence cleaved, and have a stop-transfer anchor sequence

undergo cotranslational translocation, have their C-terminus cleaved, and have a stop-transfer anchor sequence

undergo cotranslational translocation, have no signal sequence, and carry positive charges on the N-terminal side of the anchor

Explanation / Answer

Type I single pass integral membrane proteins:?

undergo posttranslational translocation, have their N-terminal signal sequence cleaved, and have a stop-transfer anchor sequence.

explanation:

With those two signals as building blocks, you can imagine a protein with a series of stop transfer and signal anchor sequences to create a whole series of back and forth transmembrane domains stitched into the membrane as if by a sewing machine. People have classified the membrane proteins into five categories:

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