TRUE/FALSE: 07. _____ J chain is used as a surrogate light chain during pre-B ce

Question

TRUE/FALSE:

07. _____ J chain is used as a surrogate light chain during pre-B cell receptor testing for successful V(D)J rearrangement.

08. _____ Binding of the antigen by antibody is stabilized by disulfide bonds.

09. _____ RAG1/2 are always expressed in B cells at high level, because B cells need RAG1/2 to constantly rearrange their V regions.

10. _____ “N” (non template) nucleotides are added by TdT.

11. _____ The 12/23 rule is applied during class switching.

12. _____ For B cells, V(D)J recombination occurs only in the bone marrow.

13. _____        The process of somatic hypermutation helps to improve specificity of the antibody

Explanation / Answer

07. false

08. false

09. false

10. true

11. false

12. true

13. true

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