Gradébook estion 2 of 7 Incorrect Sapling Learning Sort the phrases below as des
ID: 562591 • Letter: G
Question
Gradébook estion 2 of 7 Incorrect Sapling Learning Sort the phrases below as describing a competitive inhibitor, uncompetitive inhibitor, or mixed (mixed noncompetitive) inhibitor. Note that Km refers to apparent Km Competitive Inhibitor Uncompetitive Inhibitor Mixed Inhibitor structurally similar to substrate when present, Km of enzyme will increase binds either enzyme or enzyme-substrate complex when present, Km of enzyme will decrease when present, Km of binds enzyme-substrate complex only enzyme will either increase or decrease prevents substrate from binding enzyme There is a hint available! View the hint by clicking on the bottom divider bar. Click on the divider bar again to hide the hint. Close Exit e Previous e Check Answer O NextExplanation / Answer
1. Competitive inhibitor prevents the substrate from the binding enzyme. This is done by blocking binding site of the substrate. Usually, inhibitor resembles the substrate. At the same time, the enzyme can be bound to the inhibitor, substrate, neither but not both at the same time.
Competitive inhibitor increase Km because they bind to enzymes and decrease binding of the enzyme to substrate.
Thus statements which are true for competitive inhibitor -:
2. The uncompetitive inhibitor binds enzyme-substrate complex only. This occurs in reactions with two or more substrates. The binding site is only active after the enzyme has made a complex with the substrate.
Km will decrease in presence of uncompetitive inhibitor because it will increase the binding to substrate as well.
So true statements are -:
3. Mixed inhibitor represents the combination of competitive and uncompetitive inhibitor. Thus it can bind to either enzyme or enzyme-substrate complex. Thus it can either decrease the Km or increase it.
Thus true statements are -:
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